Maintaining youth and the functions of the body are possible only if one is healthy. Beta-glucan is attracting considerable attention in health conscious countries such as the United States and Japan.

Black yeast is cultured using the latest biotechnology.
The resulting thick liquid contains a large amount of evenly dispersed beta-1,3/1,6 glucan, which is currently attracting a lot of attention.
Aureo's black yeast beta-glucan.
gel form glucan image Black yeast beta-glucan is categorized as dietary fiber and a type of polysaccharide. Beta-glucan is present in the cell wall of yeasts and filamentous fungi, as well as in mushrooms (Agaricus sp., Ganoderma lucidum, etc.). The black yeast beta-glucan described here is obtained from black yeast (Latin name: Aureobasidium pullulans).

If black yeast is cultured under special conditions it forms a gel. The gel is rich in quality beta-glucan. Aureobasidium (black yeast) cultured solution was officially given food additive status in Notification No. 120, Ministry of Health and Welfare of Japan 1 (current Ministry of Health, Labour and Welfare of Japan)1 on April 16, 1996. (The notification was published in the gazette issued by the Ministry of Finance of Japan.)

1. Food additives derived from natural ingredients are listed in Notification No. 120, Ministry of Health and Welfare of Japan. Such additives are officially categorized as 'existing food additives'.
The natural culturing method ensures that

the product is gentle to the body.

Black yeast beta-glucan is produced using a culture method developed based on our unique biotechnology, and no chemical purification or extraction that uses artificial materials is carried out.

The only process that we carry out is heat sterilization. As such, black yeast beta-glucan is a truly natural, unprocessed safe food.
Structure of black yeast beta-glucan
structure of black yeast beta-glucan Beta-glucan is a type of polysaccharide, which is made up of many glucose molecules linked together.

Sugars are categorized in accordance with their structure.

A monosaccharide is made up of a single sugar molecule that cannot be broken down into simpler sugars, a disaccharide is made of two monosaccharides, and a polysaccharide is a compound made of ten or more monosaccharides.

Typical monosaccharides are glucose and fructose, a typical disaccharide is sucrose, and typical polysaccharides are glucan and dextrin.

Glucans can be divided into alpha- and beta-glucans according to the way the glucose is linked.

The structure of black yeast beta-glucan is special; it consists of a trunk (main chain) with many branches (side chains).

The structure of the trunk is "1,3", and the structure of the branch is "1,6", so it is called beta-1,3/1,6 glucan.
Development of Aureo beta-glucan
Black yeast beta-glucan is a semi-transparent gel. It was in the 1970s that a sugar refinery accidentally found a small amount of a gel (semi-liquid) in the production process.

The company analyzed the gel substance and found that it was a polysaccharide produced by a type of black yeast.
Aureo Beta Glucan
Since then, many studies have been carried out on this black yeast and methods of culturing it, and finally, a gel substance containing a large amount of beta-glucan, Aureobasidium cultured solution (Black yeast beta-glucan) was successfully produced.

We wanted to make this wonderful Aureobasidium cultured solution widely available to people, so we developed this food supplement, Aureo beta-glucan.
Notification No. 120, Ministry of Health and Welfare of Japan
Aureobasidium (black yeast) cultured solution was officially given food additive status in Notification No. 120, Ministry of Health and Welfare of Japan (current Ministry of Health, Labour and Welfare of Japan)1 on April 16, 1996. (The notification was published in the gazette issued by the Ministry of Finance of Japan.)

Moreover, the examination of a review of the safety of existing food additives by the Ministry of Health, Labour and Welfare of Japan re-confirmed the safety of Aureobasidium cultured solution (results were published in June 2004).

1. Food additives derived from natural ingredients are listed in Notification No. 120, Ministry of Health and Welfare of Japan. These additives are officially categorized as "existing food additives".

Note: Notification No. 120, Ministry of Health and Welfare of Japan verifies the safety of the product as a food, but it does not indicate that the product is a food for specified health use (i.e. it does not verify efficacy).
Information on Aureobasidium (black yeast) cultured

solution by Japan Food Additives Association

Existing food additives list number 1
Name of food additiveName: Aureobasidium cultured solution (main component: beta-1,3/1,6 glucan)
Alternative name:
Simplified name or category name
Origin, manufacturing method, and natureObtained from black yeast (Aureobasidium pullulans) cultured solution. The main component is beta-1,3/1,6 glucan.
UsageThickener, stabilizer
Product outlineThe product is a viscous liquid and is obtained from sterilized Aureobasidium pullulans (black yeast) cultured solution.
The main component is a polysaccharide called beta-1,3/1,6 glucan, and it consists of a main chain (beta-1,3), side chains (beta-1,6) and functional groups.

It is present in mushrooms and mushroom extracts, and has been attracting attention in recent years. The product is manufactured by culturing microorganisms, which is an effective way of producing this polysaccharide.
DescriptionYellow liquid
Properties and characteristicsViscous, heat-resistant, acid-resistant and salt-tolerant. Has a slight, unique taste (sour) and aroma.

Used as a thickener and is expected to be used as a taste masking agent or to have a favorable effect on health.
SolubilityReadily soluble in water. Insoluble in ethanol and fat.
PrecautionsMust be consumed immediately after opening.
StorageStore in a cool, dark place, or refrigerate.
Main foods in which this product may be usedDrinks, sauces, bread, Japanese and western confectionery, bean paste, cold sweet food, processed meat and fish, noodles, vegetable marinades, jam, baked sweets, rice cake, soft candy, processed food (film-shaped), seasoning, etc.

*This table is an extract from Explanatory Notes for Products in Existing Food Additives List, published in 1999 by Japan Food Additives Association (former subsidiary organization of the Ministry of Health and Welfare of Japan [current Ministry of Health, Labour and Welfare of Japan]).

This publication describes the nature, properties, usages and other information related to 489 food additives derived from natural ingredients, and for which use is permitted by the Ministry of Health and Welfare of Japan.
To know more about beta-glucan in general, you may visit other websites of third parties. To visit other parties's websites, click here.

Aureo Beta-Glucan: Natural Immunity Booster
Even though there are several forms of beta-glucan on the market, only one is actively potent. As we approach the wintery months ahead, it’s important to make sure your shelf contains this crucial immune enhancing compound – beta 1,3/1,6 glucan. When it comes to beta-glucans, specifically the kind derived from black yeast, there is no better immune supporter than Aureo beta-glucan.

According to studies, beta-glucans act as immunomodulator agents, meaning they regulate immune activity. Macrophages, which are immune cells that originate from bone marrow, are given direct orders to attack foreign invaders, plus they release cytokines, a critical cell-signaling chemical. Macrophages can be found in all tissues, including organ, blood, and lymph. Together, these chain reactions provide a strong barrier against many complex human ailments.

When ingested, beta-glucans can actually help bolster white blood cell count, which has been shown to help bind tumors, viruses, and stop infections from spreading. In fact, lentinan, a substance found in beta-glucan and studied at Teikyo University’s Biotechnology Research Center in Kawasaki, Japan, is showing promising results as an aide against cancer growth.

Not only does beta-glucan help your cells, but it also has a proven track for keeping bad bacteria in check. Antibiotic resistant strains are easily neutralized, providing a safe, potent, and long-term alternative to popular medications.

If an individual suffers from over-immunity, daily intake of Aureo beta-glucan can actually regulate immune cell activation. When a bacteria, virus, or parasite enters the body, beta-glucan calmly waits to mount an attack. If left unprotected, individuals with compromised immunity can develop anemia, fungal infections, low white blood cell count, and environmental sensitivities, a process characterized by early aging.

What makes Aureo beta-glucan different than other products? In essence, beta glucans are simply purified forms of yeast, but the comparison stops there. Aureo beta-glucan actually removes any leftover yeast during the purification process, which means all that is left is the active ingredient. Particle size is important when it comes to overall absorption of beta-glucan, so micronization and disaggregation are necessary steps, which prevents clumping and stagnation.

Dr. Salerno approved and heavily recommended, Aureo beta-glucan is the perfect supplement for complete immune health support.